Description

Pyridine, 2,5-Difluoro-3-Nitro- (9Ci) is a high-purity, multi-functional heterocyclic building block distinguished by its unique substitution pattern. This compound is critical for advanced organic synthesis, enabling the precise introduction of fluorine and nitro groups into complex molecular architectures. It is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and pesticides, where the fluorine atoms enhance biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and electronic materials requiring specific fluorinated aromatic components.
• Chemical Biology Probes: Useful for creating fluorescent tags or molecular probes due to the modifiable pyridine core and nitro group.

Basic Information

Product Name	Pyridine, 2,5-Difluoro-3-Nitro- (9Ci)
CAS No.	179558-82-8
Molecular Formula	C5H2F2N2O2
Molecular Weight	160.08 g/mol
Synonyms	2,5-Difluoro-3-nitropyridine; 3-Nitro-2,5-difluoropyridine; 2,5-Difluoro-3-nitro-pyridine; Pyridine, 2,5-difluoro-3-nitro-; 179558-82-8; 2,5-Difluoropyridine-3-nitro; 3-Nitro-2,5-difluoropyridine (9CI)
EINECS	Contact for details

Quality Control

Our Pyridine, 2,5-Difluoro-3-Nitro- (9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed chromatographic data are provided for traceability and to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.