Description

Prucalopride CAS NO 179474-81-8 is a highly selective serotonin 5-HT4 receptor agonist, recognized for its potent prokinetic activity. This pharmaceutical active ingredient is critical for the development of treatments for chronic constipation and related gastrointestinal motility disorders. It is primarily utilized by pharmaceutical manufacturers and research institutions engaged in the formulation of prescription medications and advanced clinical studies.

Application

• Active Pharmaceutical Ingredient (API) in prescription drugs for chronic idiopathic constipation.
• Key intermediate in the synthesis of advanced gastrointestinal prokinetic agents.
• Reference standard for analytical method development and quality control in pharmaceutical laboratories.
• Biochemical research tool for studying 5-HT4 receptor function and signaling pathways.
• Raw material for clinical trial supplies in gastroenterology research.
• Component in combination therapy development for complex motility disorders.

Basic Information

Product Name	Prucalopride
CAS No.	179474-81-8
Molecular Formula	C18H26ClN3O3
Molecular Weight	367.87 g/mol
Synonyms	Prucalopride; R 093877; R-093877; Resolor; Resotran; 4-Amino-5-chloro-2,3-dihydro-N-[1-(3-methoxypropyl)-4-piperidinyl]-7-benzofurancarboxamide; UNII-55X04QC32I
EINECS	Contact for details

Quality Control

Our Prucalopride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via HPLC, to ensure it meets high-grade pharmaceutical standards. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.