Description

tert-Butyl 4-Fluoropiperidine-1-Carboxylate is a versatile and high-purity fluorinated piperidine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a protected amine functionality and a fluorine atom, enabling precise molecular modifications for enhanced biological activity and physicochemical properties. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries, particularly for creating novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of central nervous system (CNS) drugs, kinase inhibitors, and other bioactive molecules.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where the fluoropiperidine moiety contributes to efficacy.
• Chemical Biology & Proteomics: Serves as a valuable scaffold for designing molecular probes and enzyme inhibitors.
• Material Science Research: Employed in the synthesis of specialty polymers and liquid crystals that require fluorinated components.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring a protected 4-fluoropiperidine unit.

Basic Information

Product Name	tert-Butyl 4-Fluoropiperidine-1-Carboxylate
CAS No.	178181-55-0
Molecular Formula	C10H18FNO2
Molecular Weight	203.26 g/mol
Synonyms	1-Boc-4-fluoropiperidine; 4-Fluoro-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; tert-Butyl 4-fluoropiperidine-1-carboxylate; 1-(tert-Butoxycarbonyl)-4-fluoropiperidine; N-Boc-4-fluoropiperidine; 4-Fluoro-N-Boc-piperidine; Boc-4-fluoropiperidine; 4-Fluoropiperidine-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Every batch of tert-Butyl 4-Fluoropiperidine-1-Carboxylate is produced and tested under strict quality management systems to ensure consistency and reliability for your critical research and production needs. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.