Description

L-Threoascorbic Acid-1-13C is a stable isotope-labeled analog of ascorbic acid (Vitamin C), specifically enriched with carbon-13 at the 1-position. This compound is essential for advanced research and analytical applications where precise metabolic tracing and quantification are required. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and analytical laboratories engaged in metabolomics, pharmacokinetic studies, and internal standard development for mass spectrometry.

Application

• Internal Standard for Mass Spectrometry (MS): Used as a quantitative reference standard in LC-MS and GC-MS analysis of Vitamin C and related metabolites in biological matrices.
• Metabolic Pathway Tracing: Enables precise tracking of ascorbic acid biosynthesis, turnover, and degradation in plant, animal, and human metabolic studies.
• Pharmaceutical Research: Critical for drug metabolism and pharmacokinetic (DMPK) studies of Vitamin C-based therapeutics and nutraceuticals.
• Stable Isotope Labeling Studies (SILS): Facilitates research into antioxidant mechanisms, redox biology, and collagen synthesis at the molecular level.
• Food Science & Nutrition Research: Applied in studies investigating Vitamin C stability, bioavailability, and fortification in complex food systems.
• Clinical Diagnostics Development: Serves as a key component in developing high-precision assays for Vitamin C status and deficiency.

Basic Information

Product Name	L-Threoascorbic Acid-1-13C
CAS No.	178101-88-7
Molecular Formula	C513C1H8O6
Molecular Weight	177.12 g/mol
Synonyms	L-Ascorbic Acid-1-13C; Vitamin C-1-13C; (5R)-5-[(1S)-1,2-Dihydroxyethyl]-3,4-dihydroxyfuran-2(5H)-one-1-13C; 3-Oxo-L-gulofuranolactone-1-13C; L-Threoascorbic Acid (1-13C); 13C Labeled Ascorbic Acid; 1-13C L-Ascorbic Acid; Isotopic Vitamin C
EINECS	Contact for details

Quality Control

Every batch of our L-Threoascorbic Acid-1-13C is manufactured and tested under strict quality management systems. We guarantee high chemical purity and isotopic enrichment, with comprehensive analysis performed via NMR, HPLC, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, isotopic abundance, and other critical parameters to ensure consistency for your research applications.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C under an inert atmosphere. This product is hygroscopic (moisture-sensitive) and easily oxidized; prolonged exposure to air, moisture, or elevated temperatures should be avoided to maintain stability and isotopic integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 99 atom % 13C
Chemical Purity	≥ 97%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.