Description

Gpib-Bp, Jararaca CAS NO 177530-05-1 is a high-purity synthetic peptide derived from the venom of the *Bothrops jararaca* snake. This compound is a critical research-grade biochemical tool, specifically designed for studying bradykinin-potentiating activity and its role in the renin-angiotensin system. It is essential for pharmaceutical R&D, academic research, and diagnostic development in the fields of cardiovascular biology, hypertension research, and peptide-based drug discovery.

Application

• Biochemical Research: Used as a reference standard and active agent in studies of bradykinin-potentiating peptides (BPPs) and angiotensin-converting enzyme (ACE) inhibition.
• Pharmaceutical Development: Serves as a key intermediate or lead compound in the discovery and development of novel antihypertensive and cardiovascular drugs.
• Enzyme Inhibition Studies: Employed in *in vitro* assays to investigate and quantify ACE inhibitory activity for pharmacological profiling.
• Academic & Clinical Research: Facilitates fundamental research into snake venom toxins, peptide biochemistry, and their physiological effects.
• Diagnostic Reagent Manufacturing: May be utilized in the production of specialized diagnostic kits and reagents for research purposes.

Basic Information

Product Name	Gpib-Bp, Jararaca
CAS No.	177530-05-1
Molecular Formula	C41H62N12O12S2
Molecular Weight	955.1 g/mol
Synonyms	BPP-5a; Bradykinin-Potentiating Peptide 5a; Gpib-Bp; Peptide Gpib-Bp; Jararaca BPP; Bothrops jararaca venom peptide; ACE Inhibitory Peptide; Pyr-Gly-Pro-Trp-Pro-Gln-Pro-Pro-Arg-Pro-OH (pyroglutamyl form)
EINECS	Contact for details

Quality Control

Our Gpib-Bp, Jararaca is manufactured under stringent conditions to ensure batch-to-batch consistency and high biological activity. Quality is verified through a comprehensive suite of analytical techniques including HPLC, MS, and amino acid analysis. A Certificate of Analysis (COA) detailing purity, peptide content, and biological activity is provided with each shipment to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to theoretical mass
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Biological Activity (ACE Inhibition Assay)	Reported per COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.