Description

(Rs)-3,4-DCPG is a high-purity, chiral chemical compound of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block and a potent, selective agonist for group II metabotropic glutamate receptors (mGluRs). It is primarily utilized by research institutions and pharmaceutical companies engaged in neuroscience, neuropharmacology, and the development of novel central nervous system (CNS) therapeutics.

Application

• Neuroscience Research: A key pharmacological tool for studying the function and modulation of group II mGlu receptors (mGlu2 and mGlu3) in synaptic transmission and plasticity.
• Drug Discovery & Development: Acts as a reference standard and a lead compound in the design of new therapeutics targeting neurological and psychiatric disorders.
• Biochemical Assays: Used in high-throughput screening (HTS) and in vitro assays to identify and characterize new modulators of glutamate receptor pathways.
• Preclinical Studies: Employed in animal models to investigate the therapeutic potential of mGluR modulation for conditions like anxiety, schizophrenia, and chronic pain.
• Chemical Synthesis: Serves as a sophisticated chiral intermediate for the synthesis of more complex, receptor-targeted molecules.
• Academic Research: A standard reagent in university laboratories for graduate and post-doctoral research projects focused on glutamate receptor biology.

Basic Information

Product Name	(Rs)-3,4-DCPG
CAS No.	176796-64-8
Molecular Formula	C9H11NO5
Molecular Weight	213.19 g/mol
Synonyms	(RS)-3,4-Dicarboxyphenylglycine; (RS)-3,4-DCPG; DL-3,4-Dicarboxyphenylglycine; (±)-3,4-DCPG; (RS)-3,4-Dicarboxybenzene glycine; (RS)-3,4-Dicarboxyphenylglycine; Group II mGluR Agonist (RS)-3,4-DCPG; (RS)-α-Amino-3,4-dicarboxybenzenepropanoic acid
EINECS	Contact for details

Quality Control

Every batch of (Rs)-3,4-DCPG is manufactured and analyzed under strict quality management protocols to ensure consistency and reliability for research applications. Our products undergo rigorous purity and identity verification using advanced analytical techniques. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles is provided with each shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.