Description

6-Bromo-2-Trifluoromethylquinoline is a high-value, multi-functional heterocyclic building block characterized by its bromine and trifluoromethyl substituents. This compound is essential for advanced organic synthesis, offering versatile reactivity for cross-coupling reactions and serving as a key precursor in the development of complex molecules. It is primarily utilized by research institutions and industrial R&D teams in the pharmaceutical, agrochemical, and materials science sectors to create novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Research: Serves as a key building block for developing new generation herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Material Science: Used in the research and development of organic electronic materials, including organic light-emitting diodes (OLEDs) and semiconductors, due to its electron-deficient quinoline core.
• Ligand and Catalyst Development: Employed in the design of novel ligands for transition metal catalysis and organocatalysts, enabling new synthetic methodologies.
• Chemical Biology Probes: Acts as a scaffold for creating fluorescent tags and molecular probes to study biological processes and protein interactions.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up manufacturing under cGMP conditions for clinical trial materials.

Basic Information

Product Name	6-Bromo-2-Trifluoromethylquinoline
CAS No.	176722-64-8
Molecular Formula	C10H5BrF3N
Molecular Weight	276.06 g/mol
Synonyms	2-Trifluoromethyl-6-bromoquinoline; 6-Bromo-2-(trifluoromethyl)quinoline; Quinoline, 6-bromo-2-(trifluoromethyl)-; 6-Bromo-α,α,α-trifluoro-2-quinolinemethane
EINECS	Contact for details

Quality Control

Our 6-Bromo-2-Trifluoromethylquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates for research and cGMP-compliant production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.