Description

4-Bromo-2-(Trifluoromethyl)Benzenesulfonyl Chloride is a high-value, multi-functional aromatic sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in its dual reactive sites—the sulfonyl chloride group and the bromo substituent—which enable precise, sequential functionalization for creating complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients, particularly in the synthesis of sulfonamide-based drugs and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor for the synthesis of sulfonamide drugs, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Building block for developing new herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science: Used in the production of specialty polymers and advanced materials with specific surface properties.
• Chemical Research: Versatile reagent in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Dye and Pigment Industry: Intermediate in the manufacture of complex organic dyes and colorants.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in catalytic systems.

Basic Information

Product Name	4-Bromo-2-(Trifluoromethyl)Benzenesulfonyl Chloride
CAS No.	176225-10-8
Molecular Formula	C7H3BrClF3O2S
Molecular Weight	323.51 g/mol
Synonyms	4-Bromo-2-(trifluoromethyl)benzenesulfonyl chloride; 2-Trifluoromethyl-4-bromobenzenesulfonyl chloride; 4-Bromo-alpha,alpha,α-trifluoro-o-toluenesulfonyl chloride; 1-Bromo-4-(chlorosulfonyl)-3-(trifluoromethyl)benzene; Benzenesulfonyl chloride, 4-bromo-2-(trifluoromethyl)-; 4-Bromo-2-trifluoromethylbenzenesulfonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-2-(Trifluoromethyl)Benzenesulfonyl Chloride is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, reporting key parameters such as purity (by HPLC/NMR), identity confirmation, and impurity profiles. Our quality commitment supports compliance in cGMP and ISO 9001 environments for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.