Description

4-(Trifluoromethyl)Phenyl β-D-Glucopyranosiduronic Acid is a high-purity, specialized biochemical intermediate of significant importance in modern pharmaceutical and agrochemical research. This compound serves as a critical building block for the synthesis of more complex molecules, particularly those designed for targeted biological activity. It is primarily sought after by research scientists and process chemists in the pharmaceutical, biotechnology, and agrochemical industries for developing novel active ingredients and diagnostic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting enzymes where the glucuronide moiety is essential for activity or metabolism.
• Metabolite Reference Standard: Used as an analytical standard in bioanalytical laboratories for the identification and quantification of drug metabolites in pharmacokinetic and toxicology studies.
• Bioconjugation Chemistry: Employed in the development of antibody-drug conjugates (ADCs) and other targeted therapies, where its chemical handle allows for specific linkage to biological carriers.
• Agrochemical Research: Serves as an intermediate in the development of advanced herbicides or plant growth regulators that utilize selective biochemical pathways.
• Enzyme Substrate/Inhibitor: Acts as a substrate or inhibitor for β-glucuronidase enzymes in biochemical assays and diagnostic kit development.
• Chemical Biology Probes: Utilized in the design of activity-based probes for studying glycosidase functions and mechanisms within cellular systems.

Basic Information

Product Name	4-(Trifluoromethyl)Phenyl β-D-Glucopyranosiduronic Acid
CAS No.	176223-16-8
Molecular Formula	C13H13F3O8
Molecular Weight	354.24 g/mol
Synonyms	4-(Trifluoromethyl)phenyl β-D-glucopyranosiduronic acid; p-Trifluoromethylphenyl β-D-glucuronide; 4-Trifluoromethylphenyl β-D-glucuronide; (2S,3S,4S,5R,6S)-3,4,5-Trihydroxy-6-(4-trifluoromethylphenoxy)tetrahydro-2H-pyran-2-carboxylic acid; β-D-Glucopyranosiduronic acid, 4-(trifluoromethyl)phenyl; 4-Trifluorophenyl β-D-glucuronide; p-(Trifluoromethyl)phenyl β-D-glucopyranosiduronic acid
EINECS	Contact for details

Quality Control

Our 4-(Trifluoromethyl)Phenyl β-D-Glucopyranosiduronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for research and development applications. Certificates of Analysis (COA) detailing batch-specific results are available upon request, providing full traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.