Description

(R)-Taclo CAS NO 175779-28-9 is a high-purity chiral intermediate of significant importance in modern pharmaceutical synthesis. Its value lies in its role as a key building block for the production of enantiomerically pure active pharmaceutical ingredients (APIs). This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and fine chemical industries engaged in developing and producing advanced therapeutics.

Application

• Pharmaceutical Intermediate: A critical chiral building block in the synthesis of enantiomerically pure Active Pharmaceutical Ingredients (APIs).
• Asymmetric Synthesis: Used as a precursor or reagent in catalytic asymmetric reactions to construct complex molecular architectures.
• Medicinal Chemistry Research: Serves as a valuable scaffold for drug discovery and lead optimization programs targeting specific biological pathways.
• Process Development: Employed in the scale-up and optimization of synthetic routes for new chemical entities (NCEs).
• Reference Standard: Utilized as an analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Product Name	(R)-Taclo
CAS No.	175779-28-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	(R)-Taclo; (R)-Tacrolimus derivative; (R)-Tacrolimus intermediate; (R)-FK506 intermediate; (R)-Fujimycin intermediate; (R)-Envarsus precursor; (R)-Protopic related compound
EINECS	Contact for details

Quality Control

Our (R)-Taclo is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. The product undergoes rigorous analytical testing, including chiral purity verification and impurity profiling, to meet the exacting standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing identity, purity, and specific tests are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccated environment after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.