Description

2-(2,2,2-Trifluoroethoxy)Pyridine-3-Carbonitrile is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique trifluoroethoxy substituent imparts desirable properties such as enhanced metabolic stability and lipophilicity, making it a sought-after intermediate for research and development. This compound is primarily utilized by pharmaceutical and agrochemical R&D teams for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the fluorine moiety can improve biological activity and environmental stability.
• Material Science Research: Acts as a precursor for functionalized ligands and monomers in the synthesis of specialty polymers and advanced materials.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Fluorine Chemistry Building Block: Serves as a versatile starting material for introducing the trifluoroethoxy group into more complex molecular architectures.

Basic Information

Product Name	2-(2,2,2-Trifluoroethoxy)Pyridine-3-Carbonitrile
CAS No.	175277-89-1
Molecular Formula	C8H5F3N2O
Molecular Weight	202.13 g/mol
Synonyms	3-Cyano-2-(2,2,2-trifluoroethoxy)pyridine; 2-(2,2,2-Trifluoroethoxy)nicotinonitrile; 2-(Trifluoroethoxy)pyridine-3-carbonitrile; Pyridine-3-carbonitrile, 2-(2,2,2-trifluoroethoxy)-; 175277-89-1; 2-(2,2,2-Trifluoroethoxy)-3-cyanopyridine; 3-Pyridinecarbonitrile, 2-(2,2,2-trifluoroethoxy)-
EINECS	Contact for details

Quality Control

Our production of 2-(2,2,2-Trifluoroethoxy)Pyridine-3-Carbonitrile adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO 9001 standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. The material is moisture-sensitive; ensure containers are sealed under an inert atmosphere if specified for high-purity grades.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Standard Grade)
Purity (HPLC)	≥99.0% (High Purity Grade)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.