Description

3-Chloro-2-Methyl-5-(Trifluoromethyl)Pyridine is a high-value, multi-functional heterocyclic building block essential for advanced chemical synthesis. Its unique structure, featuring both chloro and trifluoromethyl substituents on the pyridine ring, makes it a critical intermediate for introducing specific steric and electronic properties into target molecules. This compound is primarily sought after by research and development teams in the agrochemical and pharmaceutical sectors for creating novel active ingredients with enhanced efficacy and stability.

Application

• Agrochemical Intermediate: A key synthon for the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group often enhances biological activity and environmental stability.
• Pharmaceutical Building Block: Used in medicinal chemistry for the synthesis of drug candidates, particularly in areas targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Material Science Precursor: Serves as a starting material for synthesizing specialized ligands, catalysts, and functional polymers with tailored properties.
• Research & Development: Employed in academic and industrial R&D labs for method development and exploring new chemical spaces in heterocyclic chemistry.
• Custom Synthesis: A fundamental component for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for client projects.

Basic Information

Product Name	3-Chloro-2-Methyl-5-(Trifluoromethyl)Pyridine
CAS No.	175277-30-2
Molecular Formula	C7H5ClF3N
Molecular Weight	195.57 g/mol
Synonyms	2-Methyl-3-chloro-5-(trifluoromethyl)pyridine; 5-(Trifluoromethyl)-3-chloro-2-picoline; 3-Chloro-2-methyl-5-(trifluoromethyl)pyridine; 2-Picoline, 3-chloro-5-(trifluoromethyl)-; Pyridine, 3-chloro-2-methyl-5-(trifluoromethyl)-; 175277-30-2; 3-Chloro-2-methyl-5-trifluoromethylpyridine
EINECS	Contact for details

Quality Control

Our production of 3-Chloro-2-Methyl-5-(Trifluoromethyl)Pyridine adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Every lot is analyzed using advanced chromatographic and spectroscopic techniques (HPLC, GC, NMR) to confirm identity and quantify purity. Certificates of Analysis (COA) documenting all critical quality attributes are provided with each shipment. We support cGMP and ISO 9001 compliant manufacturing for applications requiring the highest quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and fluorides. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 98.0% (Standard Grade)
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.