Description

3,5-Dichloro-4-Iodobenzotrifluoride is a high-value halogenated aromatic building block, distinguished by its unique combination of chlorine, iodine, and trifluoromethyl substituents. This compound matters for its versatility as a key intermediate in advanced organic synthesis, enabling the construction of complex molecules with tailored electronic and steric properties. It is primarily needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and materials science industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of new drug candidates targeting central nervous system and metabolic diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for functional molecules in electronic displays and optoelectronic devices due to its ability to modify molecular polarity and mesomorphic properties.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed reactions (e.g., Suzuki, Sonogashira) to create complex biaryl structures.
• Organic Ligand Preparation: Utilized in synthesizing specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Fluorinated Polymer Research: Acts as a monomer or modifier in the development of high-performance polymers with enhanced chemical and thermal resistance.

Basic Information

Product Name	3,5-Dichloro-4-Iodobenzotrifluoride
CAS No.	175205-56-8
Molecular Formula	C7H2Cl2F3I
Molecular Weight	364.90 g/mol
Synonyms	4-Iodo-3,5-dichlorobenzotrifluoride; 1,3-Dichloro-2-iodo-5-(trifluoromethyl)benzene; 3,5-Dichloro-α,α,α-trifluoro-4-iodotoluene; 2-Iodo-1,3-dichloro-5-(trifluoromethyl)benzene; Benzene, 1,3-dichloro-2-iodo-5-(trifluoromethyl)-; 3,5-Dichloro-4-iodobenzotrifluoride; 3,5-Dichloro-4-iodo-α,α,α-trifluorotoluene
EINECS	Contact for details

Quality Control

Our 3,5-Dichloro-4-Iodobenzotrifluoride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.