Description

3-Amino-4-(Trifluoromethyl)Pyridine is a high-value, multi-functional heterocyclic building block characterized by its amino and trifluoromethyl substituents. This compound matters for its unique ability to impart metabolic stability, lipophilicity, and electronic properties to target molecules, making it a critical intermediate in advanced synthesis. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors, antiviral agents, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and electronic materials.
• Chemical Biology & Proteomics: Useful as a building block for designing molecular probes and activity-based protein profiling (ABPP) reagents.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research organizations for bespoke chemical synthesis projects.

Basic Information

Product Name	3-Amino-4-(Trifluoromethyl)Pyridine
CAS No.	175204-80-5
Molecular Formula	C6H5F3N2
Molecular Weight	162.11 g/mol
Synonyms	4-(Trifluoromethyl)pyridin-3-amine; 3-Amino-4-trifluoromethylpyridine; 4-(Trifluoromethyl)-3-pyridinamine; 3-Pyridinamine, 4-(trifluoromethyl)-; 3-Amino-4-(trifluoromethyl)pyridine; 175204-80-5
EINECS	Contact for details

Quality Control

Our 3-Amino-4-(Trifluoromethyl)Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.