Description

3-(Thien-2-Yl-5-(Trifluoromethyl))Isoxazole is a high-purity, heterocyclic organic compound featuring a fused isoxazole and thiophene ring system with a trifluoromethyl substituent. This unique molecular architecture makes it a critical building block in advanced organic synthesis, particularly valued for its ability to impart metabolic stability and modulate electronic properties in target molecules. It is primarily sought after by pharmaceutical R&D and agrochemical research teams for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, especially in areas targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Serves as a core scaffold for creating novel herbicides, fungicides, and insecticides with enhanced efficacy and environmental profile.
• Material Science Research: Used in the synthesis of advanced organic electronic materials, such as organic semiconductors and light-emitting diodes (OLEDs), due to its electron-deficient character.
• Chemical Biology Probe Development: Employed as a building block for creating molecular probes to study enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to fine chemical companies for use in bespoke synthesis projects and scale-up campaigns.

Basic Information

Product Name	3-(Thien-2-Yl-5-(Trifluoromethyl))Isoxazole
CAS No.	175203-89-1
Molecular Formula	C8H4F3NOS
Molecular Weight	219.18 g/mol
Synonyms	3-(5-(Trifluoromethyl)thiophen-2-yl)isoxazole; 3-(5-Trifluoromethyl-2-thienyl)isoxazole; 3-(Thiophen-2-yl-5-(trifluoromethyl))isoxazole; 2-Isoxazole, 3-[5-(trifluoromethyl)-2-thienyl]-; 175203-89-1; 3-(5-Trifluoromethylthien-2-yl)isoxazole; 3-(5-(Trifluoromethyl)-2-thienyl)-1,2-oxazole
EINECS	Contact for details

Quality Control

Our 3-(Thien-2-Yl-5-(Trifluoromethyl))Isoxazole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications requiring cGMP and ISO standards for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound should be kept under an inert atmosphere for long-term storage to maintain stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.