Description

5-Chloro-2,1,3-Benzoxadiazole-4-Sulfonyl Chloride is a high-purity, reactive chemical intermediate of significant importance in advanced organic synthesis. Its core value lies in its dual functionality, serving as a versatile building block for the construction of complex heterocyclic and sulfonamide-based compounds. This product is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and material science industries who require reliable, high-quality intermediates for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of sulfonamide-containing drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used to develop novel herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Fluorescent Probe & Dye Chemistry: Serves as a starting material for constructing benzoxadiazole-based fluorescent tags and sensors used in bioimaging and diagnostics.
• Material Science Research: Employed in the development of advanced polymers and organic electronic materials due to its electron-accepting properties.
• Cross-Coupling Reactions: Acts as an electrophilic partner in palladium-catalyzed cross-coupling reactions to form carbon-sulfur and carbon-nitrogen bonds.
• Chemical Biology: Useful for labeling biomolecules (proteins, nucleic acids) via its reactive sulfonyl chloride group for activity-based protein profiling.

Basic Information

Item	Details
Product Name	5-Chloro-2,1,3-Benzoxadiazole-4-Sulfonyl Chloride
CAS No.	175203-78-8
Molecular Formula	C6H2Cl2N2O3S
Molecular Weight	253.06 g/mol
Synonyms	4-Chloro-7-sulfonylchloride-2,1,3-benzoxadiazole; 5-Chloro-4,7-dichloro-2,1,3-benzoxadiazole (incorrect but common misnomer); 5-Chloro-2,1,3-benzothiadiazole-4-sulfonyl chloride (related analog); 4-Chloro-7-chlorosulfonyl-2,1,3-benzoxadiazole; SBD-Cl derivative; 5-Cl-BD-SO2Cl; 7-Chloro-4-sulfonylchloride-2,1,3-benzoxadiazole
EINECS	Contact for details

Quality Control

Our 5-Chloro-2,1,3-Benzoxadiazole-4-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, impurity profiles, and physical data. Our production adheres to cGMP principles where applicable, ensuring consistency and reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.