Description

2-Fluoro-3-Hydroxypyridine is a versatile fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and hydroxyl substituents, enables precise molecular modifications essential for developing high-value compounds. This intermediate is particularly valuable for researchers and manufacturers in the pharmaceutical and agrochemical sectors, where it is used to create novel active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug research.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides, where the fluorine atom can improve metabolic stability and bioavailability.
• Ligand and Catalyst Development: Serves as a precursor for constructing complex ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced electronic materials requiring specific fluorinated aromatic units.
• Chemical Biology Probes: Utilized as a scaffold for developing fluorescent tags and molecular probes for diagnostic and research applications.

Basic Information

Product Name	2-Fluoro-3-Hydroxypyridine
CAS No.	174669-74-0
Molecular Formula	C5H4FNO
Molecular Weight	113.09 g/mol
Synonyms	3-Hydroxy-2-fluoropyridine; 2-Fluoro-3-pyridinol; 2-Fluoropyridin-3-ol; 3-Pyridinol, 2-fluoro-; 174669-74-0; 2-Fluoro-3-hydroxypyridine; 2-F-3-OH-Pyridine
EINECS	Contact for details

Quality Control

Our 2-Fluoro-3-Hydroxypyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.