Description

2-Fluoro-3-Pyridylboronic Acid is a high-value organoboron building block essential for modern synthetic chemistry. This compound matters for its crucial role in the Suzuki-Miyaura cross-coupling reaction, enabling the efficient construction of complex biaryl and heterobiaryl structures. Pharmaceutical, agrochemical, and advanced materials researchers need it for developing new active ingredients and functional molecules. Its specific substitution pattern on the pyridine ring offers precise control over molecular architecture.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel active pharmaceutical ingredients (APIs), especially in kinase inhibitor and central nervous system (CNS) drug discovery.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands used in homogeneous catalysis and material science.
• Functional Material Research: Employed in the synthesis of organic electronic materials, such as those for OLEDs and semiconductors.
• Chemical Biology Probes: Utilized to create tagged molecules and probes for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: A critical reagent for custom synthesis houses and CDMOs serving the life sciences industry.

Basic Information

Product Name	2-Fluoro-3-Pyridylboronic Acid
CAS No.	174669-73-9
Molecular Formula	C5H5BFNO2
Molecular Weight	140.91 g/mol
Synonyms	(2-Fluoro-3-pyridinyl)boronic Acid; 2-Fluoro-3-pyridineboronic Acid; 3-Pyridineboronic Acid, 2-fluoro-; (2-Fluoropyridin-3-yl)boronic Acid; B-(2-Fluoro-3-pyridinyl)boronic Acid; 2-Fluoro-3-pyridylboronic acid pinacol ester (common derivative); 2-Fluoro-3-boronopyridine
EINECS	Contact for details

Quality Control

Our 2-Fluoro-3-Pyridylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are available upon request. We support compliance with relevant regulatory frameworks for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Typical 98-99%)
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.