Description

Reversin 121 CAS NO 174630-04-7 is a high-purity, small molecule compound widely recognized for its role as a potent and selective inhibitor of multidrug resistance-associated proteins (MRPs). This compound is critical for research applications where modulating cellular efflux transport is necessary. It is primarily utilized by researchers and scientists in the fields of pharmacology, oncology, and biochemistry for investigating drug resistance mechanisms and enhancing therapeutic efficacy.

Application

• Biomedical Research: Used as a key research tool to study and inhibit multidrug resistance (MDR) in cancer cell lines, aiding in the development of novel chemotherapeutic strategies.
• Pharmacology Studies: Employed in in vitro and ex vivo assays to investigate the function and inhibition of MRP1 and related transport proteins.
• Drug Discovery & Development: Serves as a reference standard and pharmacological probe in screening programs aimed at overcoming transporter-mediated drug resistance.
• Academic Research: Utilized in university and institutional labs for fundamental research on membrane transport physiology and pathophysiology.
• Diagnostic Aid Development: Potential use in developing assays to characterize the MDR phenotype of patient-derived cells.

Basic Information

Product Name	Reversin 121
CAS No.	174630-04-7
Molecular Formula	C₂₀H₂₀N₂O₅S
Molecular Weight	400.45 g/mol
Synonyms	Reversin 121; 3-[[5-[2-(3,4-Dimethoxyphenyl)ethyl]-2-methoxyphenyl]methylene]-2-indolinone; (3Z)-3-[[5-[2-(3,4-Dimethoxyphenyl)ethyl]-2-methoxyphenyl]methylene]-1,3-dihydro-2H-indol-2-one; MRP1 Inhibitor III; Multidrug Resistance-Associated Protein 1 Inhibitor, Reversin 121
EINECS	Contact for details

Quality Control

Our Reversin 121 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity confirmation and structural verification by spectroscopic methods, to ensure identity, potency, and consistency. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.