Description

2,3,4,6-Tetra-o-Acetyl-D-Mannopyranosyl Fluoride is a key fluorinated carbohydrate building block used in stereoselective glycosylation reactions. Its value lies in its role as a glycosyl donor, enabling the efficient and controlled synthesis of complex oligosaccharides and glycoconjugates. This high-purity intermediate is essential for researchers and manufacturers in pharmaceutical development, particularly for producing novel carbohydrate-based drugs, vaccines, and diagnostic agents.

Application

• Glycosylation Reagent: Acts as a crucial mannosyl donor in the synthesis of mannose-containing oligosaccharides and glycoproteins.
• Pharmaceutical Intermediates: Used in the research and production of active pharmaceutical ingredients (APIs) for antiviral, anticancer, and anti-inflammatory therapies.
• Carbohydrate Chemistry Research: A fundamental tool for academic and industrial laboratories studying glycosylation mechanisms and developing new synthetic methodologies.
• Glycoconjugate Synthesis: Enables the construction of complex molecules like glycolipids and neoglycoproteins for biological studies and diagnostic applications.
• Probe and Label Development: Serves as a starting material for creating fluorescent or bioactive carbohydrate probes used in cell biology and imaging.

Basic Information

Product Name	2,3,4,6-Tetra-o-Acetyl-D-Mannopyranosyl Fluoride
CAS No.	174511-17-2
Molecular Formula	C14H19FO9
Molecular Weight	350.29 g/mol
Synonyms	2,3,4,6-Tetra-O-acetyl-α-D-mannopyranosyl fluoride; Tetra-O-acetyl-α-D-mannopyranosyl fluoride; α-D-Mannopyranosyl fluoride tetraacetate; 1-Fluoro-2,3,4,6-tetra-O-acetyl-α-D-mannopyranose; Ac4ManαF; Mannosyl fluoride tetraacetate
EINECS	Contact for details

Quality Control

Our 2,3,4,6-Tetra-o-Acetyl-D-Mannopyranosyl Fluoride is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for research and synthesis. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant quality guidelines to support our customers in regulated development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.