Description

5-Nitro-Pyridine-2-Sulfonyl Chloride is a high-purity, reactive chemical intermediate essential for advanced organic synthesis. Its core value lies in its versatile sulfonyl chloride functionality, which enables efficient derivatization and the construction of complex molecular architectures. This compound is critically needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides with sulfonyl urea or sulfonamide moieties.
• Material Science Research: Serves as a precursor for functionalized polymers, dyes, and advanced organic electronic materials.
• Chemical Biology & Proteomics: Employed as a reactive handle for bioconjugation, labeling biomolecules, or creating activity-based probes.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses serving the life sciences sector.
• Academic & R&D Laboratories: Used in methodological development and exploratory research for new chemical reactions and catalysis.

Basic Information

Product Name	5-Nitro-Pyridine-2-Sulfonyl Chloride
CAS No.	174485-82-6
Molecular Formula	C5H3ClN2O4S
Molecular Weight	222.61 g/mol
Synonyms	2-Pyridinesulfonyl chloride, 5-nitro-; 5-Nitro-2-pyridinesulfonyl chloride; 5-Nitropyridine-2-sulfonyl chloride; 2-Chlorosulfonyl-5-nitropyridine; 5-Nitro-2-pyridylsulfonyl chloride; 5-Nitropyridin-2-ylsulfonyl chloride; 174485-82-6; 5-Nitro-2-sulfonylchloridopyridine
EINECS	Contact for details

Quality Control

Our 5-Nitro-Pyridine-2-Sulfonyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring traceability, consistency, and reliability for your research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.