Description

Cipemastat CAS NO 174265-38-4 is a potent and selective inhibitor of matrix metalloproteinases (MMPs), specifically targeting collagenase enzymes. This compound is of significant value in biochemical research for studying tissue remodeling, inflammation, and cancer metastasis pathways. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies focused on developing novel therapeutic agents for conditions involving extracellular matrix degradation.

Application

• Pharmaceutical Research & Development: As a key reference standard and tool compound for investigating MMP-mediated diseases, including arthritis, cardiovascular disorders, and tumor progression.
• Biochemical Assay Development: Used to establish and validate high-throughput screening assays for discovering new MMP inhibitors.
• Academic Studies: Employed in university and institutional labs to explore fundamental mechanisms of connective tissue breakdown and repair.
• Preclinical Studies: Serves as a pharmacological probe in animal models of cancer, fibrosis, and inflammatory diseases to understand therapeutic potential.
• Biomarker Research: Aids in studies correlating MMP activity with disease states, supporting diagnostic development.

Basic Information

Product Name	Cipemastat
CAS No.	174265-38-4
Molecular Formula	C₁₉H₂₀N₄O₃S
Molecular Weight	384.45 g/mol
Synonyms	MMP Inhibitor III; Ro 32-3555; Trocade; (2R)-N-Hydroxy-2-[[(4-methoxyphenyl)sulfonyl](3-picolyl)amino]-3-methylbutyramide; N-Hydroxy-2-((4-methoxyphenylsulfonyl)(3-pyridinylmethyl)amino)-3-methylbutyramide; 3-Methyl-2-({[4-(methyloxy)phenyl]sulfonyl}[3-pyridinylmethyl]amino)-N-hydroxybutanamide
EINECS	Contact for details

Quality Control

Our Cipemastat is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.