Description

2-Chloro-4-(Trifluoromethyl)Nicotinaldehyde is a high-value, multi-functional chemical building block characterized by its reactive aldehyde group and halogenated pyridine core. This compound matters for its critical role as a key intermediate in the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is needed by research chemists and process development teams for constructing novel active ingredients, including potential herbicides, insecticides, and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A versatile synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting various therapeutic areas.
• Agrochemical Synthesis: Serves as a crucial precursor in the manufacture of advanced herbicides and insecticides, leveraging the trifluoromethyl group for enhanced biological activity and stability.
• Chemical Research & Development: Used in academic and industrial R&D labs for constructing complex heterocyclic compounds and exploring new reaction pathways.
• Material Science: Potential intermediate for the synthesis of specialty chemicals, ligands, or functional materials requiring specific halogenated pyridine motifs.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules on various scales.

Basic Information

Product Name	2-Chloro-4-(Trifluoromethyl)Nicotinaldehyde
CAS No.	174008-48-1
Molecular Formula	C7H3ClF3NO
Molecular Weight	209.55 g/mol
Synonyms	2-Chloro-4-(trifluoromethyl)pyridine-3-carbaldehyde; 3-Formyl-2-chloro-4-(trifluoromethyl)pyridine; 2-Chloro-4-trifluoromethylnicotinaldehyde; 2-Chloro-4-(trifluoromethyl)-3-pyridinecarboxaldehyde; 174008-48-1; Nicotinaldehyde, 2-chloro-4-(trifluoromethyl)-; 2-Chloro-4-(trifluoromethyl)-3-pyridylcarboxaldehyde
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-(Trifluoromethyl)Nicotinaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere to prevent degradation from moisture and oxidation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.