Description

2-Fluoromethyl-Pyridine is a versatile fluorinated pyridine derivative, a key building block in advanced organic synthesis. Its value lies in the introduction of a reactive fluoromethyl group onto the pyridine ring, enabling the creation of complex molecules with tailored properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it serves as a critical intermediate for developing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a fluorinated pyridine moiety to modulate bioavailability, metabolic stability, or receptor binding.
• Agrochemical Synthesis: Used in the development of modern pesticides and herbicides, where the fluorine atom can enhance lipophilicity, environmental stability, and biological activity.
• Ligand and Catalyst Development: Serves as a starting material for constructing specialized ligands in coordination chemistry and catalysis, useful in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the creation of fluorinated polymers or liquid crystals, where the compound can impart unique electronic or surface properties.
• Chemical Biology Probes: Utilized in the design of molecular probes and tags for imaging and diagnostic applications, leveraging fluorine as a NMR-active nucleus (19F).

Basic Information

Product Name	2-Fluoromethyl-Pyridine
CAS No.	173974-87-3
Molecular Formula	C6H6FN
Molecular Weight	111.12 g/mol
Synonyms	2-(Fluoromethyl)pyridine; Pyridine, 2-(fluoromethyl)-; 2-Pyridinemethanol, fluoro-; α-Fluoro-2-picoline; 2-Picolyl fluoride; (Pyridin-2-yl)methyl fluoride; 2-Fluoromethylpyridine; 2-FMP
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoromethyl-Pyridine is produced and tested under a strict quality management system to ensure consistency and reliability for your critical syntheses. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our standard grade meets high-purity requirements typical for advanced intermediate use, and we can support development with custom purity specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place, away from heat sources and incompatible materials. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and concentration changes. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.