Description

3-Amino-2-Fluoro-4-Picoline is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. This compound is valued for its unique molecular architecture, which combines a reactive amino group with a fluorine atom on a pyridine scaffold, enabling precise structural modifications. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients, complex ligands, and specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and oncology.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced bioactivity and stability.
• Ligand & Catalyst Development: Serves as a versatile building block for creating complex chelating ligands and organocatalysts used in asymmetric synthesis and metal complexation.
• Material Science Research: Employed in the research and development of advanced organic electronic materials, dyes, and photoactive compounds.
• Chemical Biology Probes: Utilized as a scaffold for designing molecular probes and inhibitors for studying enzyme mechanisms and biological pathways.

Basic Information

Product Name	3-Amino-2-Fluoro-4-Picoline
CAS No.	173435-32-0
Molecular Formula	C6H7FN2
Molecular Weight	126.13 g/mol
Synonyms	2-Fluoro-3-amino-4-methylpyridine; 4-Methyl-2-fluoro-3-pyridinamine; 3-Pyridinamine, 2-fluoro-4-methyl-; 2-Fluoro-4-methylpyridin-3-amine; 3-Amino-2-fluoro-4-methylpyridine
EINECS	Contact for details

Quality Control

Our 3-Amino-2-Fluoro-4-Picoline is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP-grade starting materials and research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.