Description

10-Deacetyl Paclitaxel Ethyl Analogue is a key semi-synthetic intermediate in the production of potent anti-cancer agents. This compound matters for its critical role in the synthesis of novel taxane derivatives, which are essential for advancing oncology research and drug development. Pharmaceutical manufacturers and advanced research institutions need this high-purity intermediate to develop next-generation chemotherapeutic treatments targeting various cancers.

Application

• Pharmaceutical Intermediate: Primary use in the semi-synthetic production of paclitaxel and docetaxel analogues for cancer therapy.
• Oncology Research: Serves as a crucial building block in medicinal chemistry for developing novel taxane-based anti-cancer drugs.
• API Synthesis: Used in the multi-step synthesis of Active Pharmaceutical Ingredients (APIs) for chemotherapy.
• Biochemical Research: Employed in studies investigating microtubule stabilization and mechanisms of anti-mitotic agents.
• Process Development: Utilized in scaling up and optimizing manufacturing processes for taxane pharmaceuticals.
• Reference Standard: Acts as a high-purity analytical standard for quality control in pharmaceutical production.

Basic Information

Product Name	10-Deacetyl Paclitaxel Ethyl Analogue
CAS No.	173101-59-2
Molecular Formula	C45H51NO14
Molecular Weight	829.89 g/mol
Synonyms	10-Deacetylpaclitaxel Ethyl Ester; 10-Deacetyl Paclitaxel Ethyl Ester; 10-DAP Ethyl Ester; 10-Deacetyl-7,10-bis(2,2,2-trichloroethoxycarbonyl)paclitaxel Ethyl Ester; Taxol Intermediate; Paclitaxel Derivative; 7,10-Bis-O-(2,2,2-trichloroethoxycarbonyl)-10-deacetylpaclitaxel Ethyl Ester; 10-Deacetyl-7,10-bis(2,2,2-trichloroethoxycarbonyl)docetaxel Ethyl Ester
EINECS	Contact for details

Quality Control

Our 10-Deacetyl Paclitaxel Ethyl Analogue is manufactured under strict quality systems to ensure it meets the exacting standards required for pharmaceutical synthesis. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to verify identity, purity, and the absence of critical impurities. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with specifications. We support cGMP-compliant production for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere (e.g., nitrogen or argon) in a desiccated environment to prevent degradation. Handle and store in accordance with good laboratory practices.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.