Description

Iso Cephalomannine CAS NO 173101-54-7 is a high-purity chemical compound belonging to the taxane diterpenoid class, recognized for its structural similarity to paclitaxel. This compound is of significant interest for advanced pharmaceutical research and development, particularly in the study of novel anti-cancer agents and their mechanisms of action. It serves as a critical intermediate and reference standard for researchers and manufacturers in the oncology, biochemistry, and life science sectors.

Application

• Pharmaceutical Research & Development: As a key intermediate in the synthesis and study of complex taxane-based therapeutics.
• Oncology Drug Discovery: Used as a reference standard and building block for investigating new anti-cancer compounds and their structure-activity relationships (SAR).
• Biochemical Studies: Employed in academic and industrial laboratories to study microtubule stabilization and apoptosis pathways.
• Analytical Reference Standard: Serves as a high-purity calibrant for quality control and method development in analytical chemistry (HPLC, LC-MS).
• Process Chemistry: Utilized in the development and optimization of synthetic routes for complex natural product derivatives.

Basic Information

Product Name	Iso Cephalomannine
CAS No.	173101-54-7
Molecular Formula	C45H53NO14
Molecular Weight	831.91 g/mol
Synonyms	10-Deacetyl-7-epi-cephalomannine; 7-Epi-10-deacetylcephalomannine; Isocephalomannine; (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(Acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecah-6,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl (2R,3S)-3-(furan-2-yl)-2-hydroxy-3-[(2S,3R)-3-phenyl-2-(prop-2-enoylamino)butanoyl]oxybutanoate
EINECS	Contact for details

Quality Control

Our Iso Cephalomannine is produced under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. This product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.