Description

Octakis(6-Chloro-6-Deoxy)-γ-Cyclodextrin is a chemically modified derivative of γ-cyclodextrin, where each of the eight primary hydroxyl groups is substituted with a chlorine atom. This strategic modification significantly enhances its molecular encapsulation properties and chemical stability, making it a powerful supramolecular host for complexing a wide range of guest molecules. It is a critical advanced intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, enabling the development of novel formulations with improved solubility, stability, and bioavailability.

Application

• Pharmaceutical Research & Development: As a key building block for synthesizing more complex cyclodextrin derivatives used in drug delivery systems to enhance the solubility and stability of poorly water-soluble active pharmaceutical ingredients (APIs).
• Analytical Chemistry: Employed as a chiral selector in capillary electrophoresis (CE) and high-performance liquid chromatography (HPLC) for the separation and analysis of enantiomers.
• Catalysis & Material Science: Serves as a scaffold or ligand for constructing novel catalysts and functional materials with tailored molecular recognition properties.
• Agrochemical Formulation: Used to develop advanced formulations of pesticides and herbicides, potentially improving their efficacy, rainfastness, and environmental profile.
• Cosmetic & Personal Care: Acts as a stabilizing and solubilizing agent for fragrances, vitamins, and other sensitive active ingredients in cosmetic products.
• Food Science & Flavor Technology: Applied to encapsulate and protect volatile flavors, colors, or nutraceuticals, controlling their release and masking undesirable tastes.

Basic Information

Product Name	Octakis(6-Chloro-6-Deoxy)-γ-Cyclodextrin
CAS No.	173094-60-5
Molecular Formula	C₈₈H₁₁₂Cl₈O₄₀
Molecular Weight	2188.48 g/mol
Synonyms	γ-Cyclodextrin, 6I,6II,6III,6IV,6V,6VI,6VII,6VIII-Octachloro-6I,6II,6III,6IV,6V,6VI,6VII,6VIII-octadeoxy-; Per-6-chloro-γ-cyclodextrin; Octakis(6-chloro-6-deoxy)-γ-cyclodextrin; 6-Chloro-6-deoxy-γ-cyclodextrin, octakis derivative; γ-CD-8Cl; Heptakis(6-chloro-6-deoxy)-γ-cyclodextrin (common misnomer); 6A,6B,6C,6D,6E,6F,6G,6H-Octachloro-6A,6B,6C,6D,6E,6F,6G,6H-octadeoxy-γ-cyclodextrin
EINECS	Contact for details

Quality Control

Our Octakis(6-Chloro-6-Deoxy)-γ-Cyclodextrin is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (NMR, IR), to ensure it meets high-purity standards suitable for research and development applications. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to minimize exposure to atmospheric humidity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.