Description

Macrosphelide A CAS NO 172923-77-2 is a potent, naturally occurring macrolide compound with significant biological activity. This molecule is of high interest in pharmaceutical research and development due to its unique mechanism of action and potential as a lead structure for novel therapeutics. It is primarily utilized by research institutions and pharmaceutical companies engaged in oncology, anti-inflammatory, and anti-infective drug discovery programs. Its complex structure makes it a valuable tool for biochemical studies and target validation.

Application

• Pharmaceutical Research & Development: Serves as a key reference standard and a lead compound in the discovery of new anticancer, anti-inflammatory, and antimicrobial agents.
• Biochemical Pathway Studies: Used as a selective probe to investigate specific cellular signaling pathways and protein-protein interactions.
• Academic Research: Employed in university and institutional labs for studying macrolide biosynthesis, structure-activity relationships (SAR), and natural product chemistry.
• Preclinical Development: Acts as a critical material for in vitro and in vivo efficacy and toxicity profiling during early-stage drug candidate evaluation.
• High-Throughput Screening (HTS): Utilized as a control or benchmark compound in screening assays to identify new bioactive molecules.

Basic Information

Product Name	Macrosphelide A
CAS No.	172923-77-2
Molecular Formula	C27H38O8
Molecular Weight	490.59 g/mol
Synonyms	Macrospheride A; (-)-Macrosphelide A; (3R,4S,5S,6S,9R,10S,13S,14R,17S)-4,6,10,14-Tetrahydroxy-3,5,9,13,17-pentamethyl-18-oxabicyclo[13.2.1]octadec-7-ene-8,16-dione; 18-Oxabicyclo[13.2.1]octadec-7-ene-8,16-dione, 4,6,10,14-tetrahydroxy-3,5,9,13,17-pentamethyl-, (3R,4S,5S,6S,9R,10S,13S,14R,17S)-
EINECS	Contact for details

Quality Control

Our Macrosphelide A is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant industry standards for reference materials to support your critical research and development work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.