Description

9-Deacetyl-9-Benzoyl-10-Debenzoyltaxchinin A is a high-purity, semi-synthetic taxane derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate or reference standard in the synthesis and study of novel taxane-based chemotherapeutic agents. It is primarily utilized by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers focused on oncology drug discovery and process development. The compound's defined structure allows for precise investigation into structure-activity relationships and metabolic pathways.

Application

• Pharmaceutical Intermediate: A key building block in the synthetic pathways for novel taxane-based anticancer drugs.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control of taxane-related APIs and formulations.
• Biochemical Research: Employed in studies investigating tubulin polymerization inhibition, apoptosis mechanisms, and drug resistance in cancer cell lines.
• Process Chemistry: Serves as a precursor or model compound for optimizing fermentation, extraction, and semi-synthetic modification processes.
• Academic Research: Utilized in universities and research institutes for fundamental studies in medicinal chemistry and natural product synthesis.

Basic Information

Product Name	9-Deacetyl-9-Benzoyl-10-Debenzoyltaxchinin A
CAS No.	172486-22-5
Molecular Formula	C₄₄H₅₄O₁₃
Molecular Weight	814.90 g/mol
Synonyms	10-Deacetyl-10-benzoyltaxchinin A; 9-DAB-10-BT; Taxchinin A derivative; (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12-(Benzoyloxy)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-dodecah-4,11-dihydroxy-4a,8,13,13-tetramethyl-7-oxo-5H-6,12b-epoxycyclodeca[3,4]benz[1,2-b]oxet-9-yl acetate; 9-Deacetyl-9-benzoyltaxchinin A; 10-Debenzoyltaxchinin A derivative
EINECS	Contact for details

Quality Control

Our 9-Deacetyl-9-Benzoyl-10-Debenzoyltaxchinin A is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization using techniques including HPLC, NMR, and MS to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, which includes batch-specific data on assay, related substances, and residual solvents. Our quality commitment aligns with the standards expected for pharmaceutical research materials.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing under inert atmosphere at -20°C to maximize stability. Keep the container sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Single Unknown Impurity	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.