Description

Imperatoxin A is a high-purity, biologically active peptide toxin isolated from scorpion venom. This compound is of significant interest in biochemical and pharmacological research due to its potent and specific activity as a ryanodine receptor (RyR) modulator. It serves as a critical tool for researchers in neuroscience, cardiac physiology, and muscle biology, enabling the study of intracellular calcium signaling pathways. Our supply ensures consistent quality and reliable availability for global research and development applications.

Application

• Biochemical Research: A key pharmacological tool for studying the structure and function of ryanodine receptor (RyR) calcium release channels.
• Neuroscience Studies: Used to investigate calcium-induced calcium release (CICR) mechanisms in neuronal cells and synaptic plasticity.
• Cardiac Physiology Research: Applied in models to understand calcium handling in cardiomyocytes and its role in cardiac muscle contraction and arrhythmias.
• Skeletal Muscle Research: Utilized to probe excitation-contraction coupling and calcium signaling dynamics in muscle cells.
• Pharmaceutical Discovery: Serves as a reference standard and probe in drug discovery programs targeting calcium channelopathies.
• Toxicology & Venom Studies: Used as a reference compound in the study of scorpion venom components and their mechanisms of action.

Basic Information

Product Name	Imperatoxin A
CAS No.	172451-37-5
Molecular Formula	C254H383N73O70S6
Molecular Weight	5878.6 g/mol
Synonyms	Imperatoxin A; Imperatoxin I; Peptide toxin Imperatoxin A; RyR modulator Imperatoxin A; α-Imperatoxin A; Scorpion toxin Imperatoxin A; ITX-A
EINECS	Contact for details

Quality Control

Every batch of Imperatoxin A is subjected to rigorous analytical testing to ensure identity, purity, and biological activity. Our quality assurance protocols are designed to meet the exacting standards of research and pharmaceutical development. A comprehensive Certificate of Analysis (COA) detailing purity (by HPLC), molecular weight confirmation (by Mass Spectrometry), and bioactivity is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Aliquot to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (Mass Spec)	Consistent with molecular weight
Purity (HPLC)	≥ 95%
Biological Activity	Verified by RyR binding/functional assay
Water Content (KF)	≤ 5.0 %
Endotoxin Level	< 1.0 EU/μg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.