Description

Pkc β Pseudosubstrate CAS NO 172308-76-8 is a specialized biochemical compound designed as a potent and selective inhibitor of protein kinase C (PKC) beta isoforms. This high-purity reagent is critical for advanced life science research, enabling precise investigation of PKC-mediated signaling pathways. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and diagnostic developers focused on oncology, neuroscience, and metabolic disorders.

Application

• Biochemical Research: A key tool for studying the specific roles of PKCβ isoforms in cellular signal transduction, differentiation, and apoptosis.
• Drug Discovery & Development: Used in high-throughput screening (HTS) assays and target validation studies for therapeutic programs targeting PKC, particularly in cancer and inflammatory diseases.
• Enzymology Studies: Serves as a competitive pseudosubstrate inhibitor in kinetic assays to determine PKC enzyme activity and inhibition constants (Ki).
• Neuroscience Research: Applied in models to understand PKCβ involvement in neuronal function, synaptic plasticity, and related neurological conditions.
• Diagnostic Kit Development: Incorporated as a critical component in ELISA and other assay kits designed to measure PKC activity in clinical and research samples.

Basic Information

Product Name	Pkc β Pseudosubstrate
CAS No.	172308-76-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	PKCβ Pseudosubstrate Inhibitor; PKC Beta Pseudosubstrate; Protein Kinase C Beta Inhibitor Peptide; PKCβ (19-31); PKC Beta (19-31); RFARKGALRQKNV; Pseudosubstrate Peptide of PKC Beta
EINECS	Contact for details

Quality Control

Our Pkc β Pseudosubstrate is manufactured under stringent conditions to ensure batch-to-batch consistency and high biological activity. Each lot undergoes rigorous analytical testing, including purity assessment by HPLC and identity confirmation by mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, peptide content, and performance data is provided with every shipment to support your critical research and development work.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 70% (by weight)
Solubility	Soluble in water or aqueous buffer
Biological Activity (IC50)	Specification available upon request

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.