Description

Tryprostatin A is a prenylated indole alkaloid of significant interest in biochemical and pharmacological research. This compound is valued for its role as a potent and specific inhibitor of mammalian cell cycle progression, making it a critical tool for studying microtubule dynamics and mitosis. It is primarily utilized by researchers in pharmaceutical R&D, biotechnology, and academic institutions focused on oncology, cell biology, and drug discovery programs.

Application

• Biochemical Research: Used as a specific pharmacological agent to inhibit microtubule assembly and study mitotic arrest in mammalian cells.
• Oncology & Cancer Research: Serves as a valuable reference compound and probe for investigating novel anti-mitotic drug targets and pathways.
• Cell Biology Studies: Employed to elucidate mechanisms of cell cycle control, spindle formation, and chromosome segregation.
• Pharmaceutical Development: Acts as a lead compound or structural template in the discovery and optimization of new chemotherapeutic agents.
• Academic Research: Utilized in university and institutional labs for fundamental studies in natural product chemistry and bioactivity.

Basic Information

Product Name	Tryprostatin A
CAS No.	171864-80-5
Molecular Formula	C₂₂H₂₇N₃O₃
Molecular Weight	381.47 g/mol
Synonyms	Tryprostatin A; NSC 654663; 1H-Indole-3-acetic acid, α-(1,1-dimethylethyl)-2,3-dihydro-6-methoxy-N-(phenylmethyl)-β-oxo-; 6-Methoxy-3-(2-methyl-1-oxobutyl)-1-(phenylmethyl)-1H-indole-2-carboxylic acid, 1,1-dimethylethyl ester; Benzyl 6-methoxy-3-(2-methyl-1-oxobutyl)-1H-indole-2-carboxylate, tert-butyl ester
EINECS	Contact for details

Quality Control

Our Tryprostatin A is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and reliability for research applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your regulatory and documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.