Description

Methyltadalafil is a synthetic organic compound belonging to the class of phosphodiesterase type 5 (PDE5) inhibitors. This high-purity intermediate is of significant value in pharmaceutical research and development, particularly for investigating novel therapeutic pathways. It is primarily utilized by R&D laboratories and chemical manufacturers focused on producing active pharmaceutical ingredients (APIs) and fine chemicals. The compound's defined structure makes it a critical building block for specialized synthesis.

Application

• Pharmaceutical Intermediate: Key precursor in the research and synthesis of novel PDE5 inhibitor compounds and related active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard or tool compound in enzymatic studies targeting phosphodiesterase activity.
• Fine Chemical Synthesis: Serves as a specialized building block for constructing complex molecular architectures in medicinal chemistry projects.
• Analytical Standard: Employed in quality control laboratories for method development, validation, and as a purity benchmark via HPLC or LC-MS.
• Academic Research: Utilized in university and institutional labs for pharmacological studies and structure-activity relationship (SAR) exploration.

Basic Information

Product Name	Methyltadalafil
CAS No.	171488-11-2
Molecular Formula	C₂₃H₂₀N₄O₄
Molecular Weight	416.43 g/mol
Synonyms	Methyl Tadalafil; N-Methyl Tadalafil; 2-Methyl Tadalafil; (6R,12aR)-2-Methyl-6-(1,3-benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione; Methylated Tadalafil Analog; Tadalafil Methyl Derivative
EINECS	Contact for details

Quality Control

Our Methyltadalafil is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity determination and spectroscopic methods for structural confirmation, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.