Description

Octakis(6-Amino-6-Deoxy)-γ-Cyclodextrin is a chemically modified, water-soluble cyclic oligosaccharide derivative featuring eight primary amino groups, which significantly enhances its molecular encapsulation and binding capabilities. This functionalization makes it a powerful supramolecular host for a wide range of guest molecules, driving innovation in advanced material science and pharmaceutical development. It is a critical reagent for researchers and manufacturers in the pharmaceutical, biotechnology, and chemical synthesis sectors seeking to improve drug solubility, stability, and targeted delivery.

Application

• Pharmaceutical Solubility & Bioavailability Enhancement: Acts as a complexing agent to increase the aqueous solubility and dissolution rate of poorly soluble active pharmaceutical ingredients (APIs).
• Drug Delivery Systems: Serves as a functional building block for constructing sophisticated drug carriers, including polymeric nanoparticles and targeted delivery platforms, leveraging its amino groups for further conjugation.
• Catalyst & Enzyme Mimics: Utilized in supramolecular catalysis, where its cavity provides a unique micro-environment to facilitate or modify chemical reactions, mimicking enzyme function.
• Chemical Sensors & Separation Science: Employed in the development of selective sensors and as a chiral stationary phase modifier in chromatography for the separation of enantiomers.
• Gene Delivery: Investigated as a component in non-viral gene delivery vectors, where its cationic nature helps condense and protect nucleic acids.
• Cosmetic Formulations: Used to stabilize sensitive active ingredients, control odor, and enhance the performance of cosmetic products.

Basic Information

Product Name	Octakis(6-Amino-6-Deoxy)-γ-Cyclodextrin
CAS No.	171283-79-7
Molecular Formula	C₈₈H₁₆₀N₈O₆₄
Molecular Weight	~2370.2 g/mol
Synonyms	6A,6B,6C,6D,6E,6F,6G,6H-Octaamino-6A,6B,6C,6D,6E,6F,6G,6H-octadeoxy-γ-cyclodextrin; γ-Cyclodextrin, octakis(6-amino-6-deoxy)-; Per-6-amino-γ-cyclodextrin; 6I-Octaamino-6I-octadeoxy-γ-cyclodextrin; Amino-γ-CD; 6-NH2-γ-CD; Octa(6-amino-6-deoxy)-γ-cyclodextrin
EINECS	Contact for details

Quality Control

Our Octakis(6-Amino-6-Deoxy)-γ-Cyclodextrin is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and commercial applications. A Certificate of Analysis (COA) detailing specific results for purity, residual solvents, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation and clumping. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 10 ppm
Bacterial Endotoxins	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.