Description

2,6-Difluoropyridine-3-Carboxylic Acid is a high-value fluorinated pyridine derivative serving as a critical building block in advanced organic synthesis. Its unique structure, featuring two fluorine atoms and a carboxylic acid group on the pyridine ring, makes it an essential precursor for creating complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and anti-infective research.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis projects requiring specific fluorinated heterocyclic architectures.

Basic Information

Product Name	2,6-Difluoropyridine-3-Carboxylic Acid
CAS No.	171178-50-0
Molecular Formula	C6H3F2NO2
Molecular Weight	159.09 g/mol
Synonyms	3-Carboxy-2,6-difluoropyridine; 2,6-Difluoronicotinic Acid; 2,6-Difluoropyridine-3-carboxylic acid; 2,6-Difluoro-3-pyridinecarboxylic Acid; 2,6-Difluoronictonic Acid; Difluoropyridinecarboxylic Acid; 171178-50-0
EINECS	Contact for details

Quality Control

Our 2,6-Difluoropyridine-3-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates under GMP or ISO guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.