Description

7-Fluoropyrido[4,3-D]Pyrimidin-4(1H)-One is a high-purity fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound serves as a critical intermediate for the development of novel pharmaceutical candidates, particularly in kinase inhibitor research and other targeted therapeutic areas. It is essential for medicinal chemists and R&D departments in the pharmaceutical, biotechnology, and fine chemical industries seeking to introduce specific fluorinated pyridopyrimidine scaffolds into their molecular libraries.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of small molecule drugs, especially kinase inhibitors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to explore new chemical entities.
• Biochemical Tool Compound: Serves as a precursor for labeled probes or active pharmaceutical ingredients (APIs) in biological testing.
• Fine Chemical Synthesis: Employed in multi-step synthetic routes to construct complex, fluorinated heterocyclic systems.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations offering custom synthesis and process development services.
• Academic Research: Utilized in university and institutional labs for pioneering studies in organic and medicinal chemistry.

Basic Information

Product Name	7-Fluoropyrido[4,3-D]Pyrimidin-4(1H)-One
CAS No.	171178-37-3
Molecular Formula	C7H4FN3O
Molecular Weight	165.12 g/mol
Synonyms	7-Fluoropyrido[4,3-d]pyrimidin-4(1H)-one; 7-Fluoro-1H-pyrido[4,3-d]pyrimidin-4-one; 7-Fluoro-4-hydroxy-pyrido[4,3-d]pyrimidine; 7-Fluoro-1,4-dihydro-pyrido[4,3-d]pyrimidin-4-one; 171178-37-3; 7-Fluoro-1H-pyrido[4,3-d]pyrimidin-4-ol; 7-Fluoropyrido[4,3-d]pyrimidin-4-ol
EINECS	Contact for details

Quality Control

Our 7-Fluoropyrido[4,3-D]Pyrimidin-4(1H)-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider conditions under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.