Description

(5S,6R,15R)-5,6,15-Trihydroxy-7,9,13-trans-11-cis-Eicosatetraenoic Acid CAS NO 171030-11-8 is a specialized eicosanoid derivative, specifically a trihydroxy eicosatetraenoic acid (THETA) with defined stereochemistry. This compound is a key intermediate and reference standard in lipid mediator research, playing a crucial role in understanding inflammatory and resolution pathways. It is essential for pharmaceutical R&D, analytical laboratories, and academic institutions focused on the biochemistry of arachidonic acid metabolites and the development of novel therapeutic agents.

Application

• Biochemical Research Standard: Serves as a high-purity reference compound for the study of lipoxin and eicosanoid biosynthesis and signaling pathways.
• Pharmaceutical Development: Used as a critical intermediate or analytical standard in the research and development of anti-inflammatory and pro-resolving lipid-based therapeutics.
• Cell Signaling Studies: Applied in in vitro and ex vivo assays to investigate the biological effects of specific hydroxy-eicosatetraenoic acid (HETE) isomers on cellular function.
• Analytical Method Development: Employed as a certified reference material (CRM) to validate and calibrate analytical methods such as LC-MS/MS and HPLC for lipidomics.
• Academic Research: A vital tool for universities and research institutes exploring the complex roles of specialized pro-resolving mediators (SPMs) in physiology and disease.

Basic Information

Item	Detail
Product Name	(5S,6R,15R)-5,6,15-Trihydroxy-7,9,13-trans-11-cis-Eicosatetraenoic Acid
CAS No.	171030-11-8
Molecular Formula	C₂₀H₃₂O₅
Molecular Weight	352.47 g/mol
Synonyms	5(S),6(R),15(R)-TriHETE; 5,6,15-Trihydroxy-7,9,13-trans-11-cis-eicosatetraenoic acid; (5S,6R,15R)-Trihydroxy-7,9,13-trans-11-cis-eicosatetraenoic acid; 5,6,15-TriHETE; 5,6,15-Trihydroxyeicosatetraenoic acid; Lipoxin pathway intermediate; 5(S),6(R),15(R)-Trihydroxyeicosatetraenoic acid
EINECS	Contact for details

Quality Control

Every batch of our (5S,6R,15R)-5,6,15-Trihydroxy-7,9,13-trans-11-cis-Eicosatetraenoic Acid is manufactured and analyzed under strict quality management systems to ensure high purity, identity, and batch-to-batch consistency, meeting the exacting requirements of research and development. Certificates of Analysis (COA) detailing purity (by HPLC), stereochemical identity, and other critical parameters are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term storage, keep at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and hydrolysis. The product is hygroscopic and moisture-sensitive; allow the sealed vial to equilibrate to room temperature before opening to avoid condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to reference standard
Identification (Optical Rotation)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solvent Residue (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.