Description

2-(Trifluoromethyl)Pyridin-4-Ol is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced chemical synthesis. Its unique trifluoromethyl-substituted pyridinol structure offers exceptional electronic and steric properties for modulating the activity of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients with enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and central nervous system (CNS) targeted drugs.
• Agrochemical Synthesis: Used in the research and production of modern pesticides and herbicides, where the trifluoromethyl group contributes to improved lipophilicity and biological activity.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science: Employed in the synthesis of advanced organic electronic materials and liquid crystals.
• Chemical Research: A versatile reagent for medicinal chemistry and process chemistry research in both academic and industrial R&D settings.

Basic Information

Product Name	2-(Trifluoromethyl)Pyridin-4-Ol
CAS No.	170886-13-2
Molecular Formula	C6H4F3NO
Molecular Weight	163.10 g/mol
Synonyms	4-Hydroxy-2-(trifluoromethyl)pyridine; 2-(Trifluoromethyl)-4-pyridinol; 4-Pyridinol, 2-(trifluoromethyl)-; 2-Trifluoromethylpyridin-4-ol; 2-Trifluoromethyl-4-hydroxypyridine; 4-Hydroxy-α,α,α-trifluoro-2-picoline
EINECS	Contact for details

Quality Control

Our 2-(Trifluoromethyl)Pyridin-4-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide full traceability and detailed Certificates of Analysis (COA) for every shipment, supporting your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is moisture-sensitive (hygroscopic). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.