Description

1-(4-Chloro-Phenyl)-4,4-Difluoro-Butane-1,3-Dione is a specialized fluorinated diketone building block of significant interest in advanced organic synthesis. Its unique structure, featuring both a chloro-phenyl group and a difluoro-diketone moiety, makes it a versatile precursor for creating complex molecules with tailored properties. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly those requiring fluorinated scaffolds to modulate bioavailability, metabolic stability, and binding affinity.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the introduction of fluorine atoms can enhance biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for β-diketone ligands used in coordination chemistry and catalysis, especially for metals where fluorinated ligands offer unique reactivity.
• Material Science Research: Employed in the synthesis of fluorinated polymers and advanced organic materials with specific optical or electronic properties.
• Chemical Research & Development: A valuable building block in medicinal chemistry and process chemistry for exploring new synthetic routes and creating compound libraries.

Basic Information

Product Name	1-(4-Chloro-Phenyl)-4,4-Difluoro-Butane-1,3-Dione
CAS No.	170570-76-0
Molecular Formula	C10H7ClF2O2
Molecular Weight	232.61 g/mol
Synonyms	4'-Chloro-4,4-difluoro-1-phenylbutane-1,3-dione; 1-(4-Chlorophenyl)-4,4-difluorobutane-1,3-dione; 4,4-Difluoro-1-(4-chlorophenyl)-1,3-butanedione; p-Chloro-4,4-difluorobenzoylacetone; 4-Chlorophenyl 4,4-difluoro-3-oxobutanoate (tautomer); DFB-CP; 170570-76-0
EINECS	Contact for details

Quality Control

Our 1-(4-Chloro-Phenyl)-4,4-Difluoro-Butane-1,3-Dione is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container should be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.