Description

2'H-Androst-2-Eno[3,2-C]Pyrazol-5'(1'H)-One, 17-Hydroxy-17-(Methyl-D3)-, (5α,17β)- (9Ci) is a high-purity, deuterated steroid derivative of significant interest in advanced pharmaceutical research and development. This compound is valued for its role as a key synthetic intermediate or reference standard in the creation of novel therapeutic agents, particularly where metabolic stability and pharmacokinetic studies are critical. It is primarily utilized by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers focused on endocrinology, oncology, and metabolic disease research.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for analytical method development, validation, and quality control in drug substance manufacturing.
• Deuterated Drug Intermediate: Serves as a crucial building block in the synthesis of deuterium-labeled active pharmaceutical ingredients (APIs) to enhance metabolic stability and alter pharmacokinetic profiles.
• Metabolic Pathway Tracer: Employed in preclinical and clinical research to study steroid hormone metabolism, distribution, and excretion using mass spectrometry techniques.
• Biochemical Research Reagent: Utilized in vitro and in vivo studies to investigate steroid receptor interactions, enzyme inhibition, and signal transduction pathways.
• Process Chemistry Development: Acts as a high-value intermediate in the scale-up and optimization of synthetic routes for complex steroid-based therapeutics.

Basic Information

Product Name	2'H-Androst-2-Eno[3,2-C]Pyrazol-5'(1'H)-One, 17-Hydroxy-17-(Methyl-D3)-, (5α,17β)- (9Ci)
CAS No.	170082-17-4
Molecular Formula	C21H29D3N2O2
Molecular Weight	347.51 g/mol
Synonyms	17β-Hydroxy-17-(methyl-d3)-2'H-androst-2-eno[3,2-c]pyrazol-5'(1'H)-one; 17-(Methyl-d3)-17β-hydroxy-5α-androst-2-eno[3,2-c]pyrazol-5-one; Deuterated Stanozolol Metabolite; (5α,17β)-17-Hydroxy-17-(trideuteriomethyl)-2'H-androst-2-eno[3,2-c]pyrazol-5'(1'H)-one; 17β-Hydroxy-17α-methyld3-5α-androstano[3,2-c]pyrazole; Androstano[3,2-c]pyrazole-17β-ol, 17α-methyld3- derivative
EINECS	Contact for details

Quality Control

Every batch of 2'H-Androst-2-Eno[3,2-C]Pyrazol-5'(1'H)-One, 17-Hydroxy-17-(Methyl-D3)-, (5α,17β)- (9Ci) is manufactured and tested under a strict quality management system. We provide comprehensive analytical documentation to support your regulatory and research requirements. Certificates of Analysis (COA) detailing purity, isotopic enrichment, and impurity profiles are supplied with each shipment, ensuring traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment and handled under appropriate conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Deuterium Enrichment (NMR/MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.