Description

Clonazepam-D4 CAS NO 170082-15-2 is a stable isotope-labeled analog of the benzodiazepine drug Clonazepam, where four hydrogen atoms are replaced by deuterium. This high-purity reference standard is critical for ensuring the accuracy and reliability of quantitative analytical methods. It is an essential tool for researchers and quality control laboratories in the pharmaceutical and forensic science industries who require precise internal standards for mass spectrometry.

Application

• Used as an internal standard for the precise quantification of Clonazepam in biological matrices via LC-MS/MS and GC-MS.
• Critical component in pharmaceutical research and development for pharmacokinetic and metabolic studies.
• Essential for forensic and clinical toxicology laboratories conducting drug screening and confirmation assays.
• Supports method development and validation in analytical chemistry to meet regulatory compliance (e.g., FDA, EMA).
• Facilitates doping control analysis in sports to detect benzodiazepine use.
• Enables quality control testing in pharmaceutical manufacturing to ensure drug purity and consistency.

Basic Information

Product Name	Clonazepam-D4
CAS No.	170082-15-2
Molecular Formula	C15H6D4ClN3O3
Molecular Weight	319.73 g/mol
Synonyms	5-(2-Chlorophenyl)-1,3-dihydro-7-nitro-2H-1,4-benzodiazepin-2-one-d4; Clonazepam (phenyl-d4); Clonazepam-d4 (Major); [2H4]-Clonazepam; 1,4-Benzodiazepin-2-one, 5-(2-chlorophenyl)-1,3-dihydro-7-nitro-, (phenyl-d4); Deuterated Clonazepam; Klonopin-d4
EINECS	Contact for details

Quality Control

Our Clonazepam-D4 is manufactured under strict quality systems to ensure the highest isotopic and chemical purity required for analytical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing results for assay, isotopic enrichment, and impurity profiles. We adhere to relevant industry standards to support our clients' regulatory and research needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity	≥ 98 atom % D
Chemical Purity	≥ 95%
Water Content	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.