Description

4-(Trifluoromethoxy)Phenylmagnesium Bromide is a highly reactive organometallic reagent, specifically a Grignard reagent, widely used in organic synthesis. Its core value lies in its ability to introduce the versatile 4-(trifluoromethoxy)phenyl group into molecular frameworks, a key structural motif for modulating the physicochemical properties of target compounds. This reagent is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials industries, enabling the synthesis of complex molecules for drug discovery, crop protection agents, and specialty chemicals.

Application

• Pharmaceutical intermediate synthesis for active pharmaceutical ingredients (APIs).
• Building block for agrochemicals, including herbicides and fungicides.
• Key reagent in the development of liquid crystal materials for electronic displays.
• Precursor for ligands used in catalysis and material science.
• Introduction of the trifluoromethoxy group into aromatic systems for medicinal chemistry optimization.
• Laboratory-scale research and process development in fine chemical synthesis.

Basic Information

Product Name	4-(Trifluoromethoxy)Phenylmagnesium Bromide
CAS No.	169222-42-8
Molecular Formula	C7H4BrF3MgO
Molecular Weight	265.31 g/mol
Synonyms	4-(Trifluoromethoxy)phenylmagnesium bromide; [4-(Trifluoromethoxy)phenyl]magnesium bromide; 1-Bromo-4-(trifluoromethoxy)benzene magnesium; (4-Trifluoromethoxyphenyl)magnesium bromide; Grignard reagent 4-(Trifluoromethoxy)phenyl; 4-(Trifluoromethoxy)phenyl magnesium bromide solution; p-(Trifluoromethoxy)phenylmagnesium bromide
EINECS	Contact for details

Quality Control

Our 4-(Trifluoromethoxy)Phenylmagnesium Bromide is manufactured under strict quality protocols to ensure batch-to-batch consistency and high reactivity. The product undergoes rigorous analytical testing, including titration for Grignard concentration and GC/HPLC analysis for purity and solvent content. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. This material is hygroscopic (moisture-sensitive) and easily oxidized; it must be stored under an inert atmosphere (argon or nitrogen) in a cool, dry place. For solutions, store at recommended temperatures (typically 2-8°C or as specified) and ensure containers are properly sealed to prevent ingress of moisture and air.

Specification

Item	Specification
Appearance	Colorless to brownish solution
Concentration (in THF or Ether)	0.5 M - 2.0 M (Typical)
Assay (Titration)	≥ 95%
Purity (GC/HPLC)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.