Description

Skf-97541 Hydrochloride is a potent and selective GABAB receptor antagonist used extensively in neuroscience and pharmacological research. This compound is critical for studying the role of GABAB receptors in neurological pathways, synaptic transmission, and potential therapeutic targets. It is an essential research-grade chemical for pharmaceutical R&D, academic institutions, and contract research organizations (CROs) focused on central nervous system (CNS) disorders, receptor characterization, and drug discovery programs.

Application

• Neuroscience Research: A key tool for investigating the function and modulation of GABAB receptors in the central and peripheral nervous systems.
• Pharmacological Studies: Used in in vitro and in vivo assays to antagonize GABAB receptor activity and study downstream effects.
• Drug Discovery & Development: Serves as a reference standard and pharmacological probe in high-throughput screening (HTS) and lead optimization for CNS-targeted therapeutics.
• Academic & Institutional Research: Employed in university and government labs for fundamental research on neurotransmission, synaptic plasticity, and behavior.
• Biochemical Assay Development: Utilized in the development and validation of receptor binding, functional, and signaling assays.

Basic Information

Product Name	Skf-97541 Hydrochloride
CAS No.	168977-94-4
Molecular Formula	C10H15ClN2O3 • HCl
Molecular Weight	291.15 g/mol
Synonyms	SKF-97541 HCl; 3-Aminopropyl(methyl)phosphinic acid hydrochloride; CGP 35348 hydrochloride; GABAB receptor antagonist SKF-97541; (3-Aminopropyl)(methyl)phosphinic acid hydrochloride; SKF 97541; 3-APMPA hydrochloride
EINECS	Contact for details

Quality Control

Our Skf-97541 Hydrochloride is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to guarantee traceability and compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.