Description

ω-Conotoxin Mviic is a highly selective and potent peptide neurotoxin derived from the venom of marine cone snails. This compound is a crucial pharmacological tool for the study and characterization of N-type voltage-gated calcium channels (Cav2.2). It is essential for researchers and developers in neuroscience and drug discovery, providing a reliable standard for electrophysiology studies, channel subtype validation, and the development of novel therapeutics for chronic pain and neurological disorders.

Application

• Neuroscience Research: A primary tool for blocking N-type calcium channels in electrophysiological experiments to study synaptic transmission and neuronal excitability.
• Drug Discovery & Development: Used as a reference standard in high-throughput screening assays to identify and characterize new analgesics and neuroprotective agents targeting Cav2.2 channels.
• Channel Pharmacology: Critical for the functional characterization and subtype discrimination of voltage-gated calcium channels in recombinant cell systems and native tissues.
• Biochemical Studies: Employed in binding assays (e.g., radioligand displacement) to determine receptor affinity and study channel structure-function relationships.
• Academic & Institutional Research: Supports fundamental research in universities and institutes focused on pain pathways, neurotransmitter release, and neurological disease mechanisms.
• Biotechnology Reagents: Incorporated into specialized reagent kits for calcium channel analysis and related diagnostic development.

Basic Information

Product Name	ω-Conotoxin Mviic
CAS No.	168831-68-3
Molecular Formula	C102H164N32O32S7
Molecular Weight	~2639.1 g/mol
Synonyms	ω-Conotoxin MVIIC; Conotoxin MVIIC; ω-Conotoxin MVIIC; MVIIC; ω-CTx-MVIIC; Cav2.2 Channel Blocker; N-type Calcium Channel Blocker MVIIC; SNX-230; Synthetic ω-Conotoxin MVIIC
EINECS	Contact for details

Quality Control

Every batch of ω-Conotoxin Mviic is produced and analyzed under strict quality protocols to ensure the highest standards of purity and biological activity for research applications. Our quality assurance includes comprehensive testing for identity, purity, and potency. Certificates of Analysis (COA) detailing lot-specific results from HPLC, MS, and functional activity assays are available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Biological Activity (IC50)	Specified per batch (nM range)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.