Description

Octakis-6-Iodo-6-Deoxy-γ-Cyclodextrin is a fully substituted, per-iodinated derivative of γ-cyclodextrin, a cyclic oligosaccharide composed of eight glucose units. This chemical modification introduces eight iodine atoms, significantly enhancing its properties as a versatile host molecule for forming inclusion complexes with a wide range of guest compounds. It is particularly valuable in advanced research and development for applications requiring precise molecular encapsulation and stabilization. This product is essential for scientists and engineers in the pharmaceutical, agrochemical, and material science sectors.

Application

• Pharmaceutical Research: As a host compound for solubility enhancement, stabilization, and controlled release studies of poorly soluble active pharmaceutical ingredients (APIs).
• Catalysis & Synthesis: Serving as a molecular scaffold or catalyst support in organic synthesis due to its well-defined cavity and iodine substituents.
• Analytical Chemistry: Utilized as a chiral selector or stationary phase modifier in chromatographic separations (HPLC, CE) for enantiomer resolution.
• Material Science: A building block for creating functionalized polymers, supramolecular assemblies, and nano-carriers with specific host-guest properties.
• Agrochemical Formulation: Investigating its use to improve the stability, solubility, and bioavailability of agrochemicals.
• Diagnostic Agent Development: Potential use in the design of contrast agents or probes for imaging techniques, leveraging the iodine atoms.

Basic Information

Product Name	Octakis-6-Iodo-6-Deoxy-γ-Cyclodextrin
CAS No.	168296-33-1
Molecular Formula	C~48~H~64~I~8~O~32~
Molecular Weight	~ 2656.6 g/mol
Synonyms	Per-6-iodo-γ-cyclodextrin; γ-Cyclodextrin, octakis(6-deoxy-6-iodo)-; Octakis(6-deoxy-6-iodo)-γ-cyclodextrin; 6^I-OI-γ-CD; 6-Periodo-γ-cyclodextrin; Iodinated Gamma Cyclodextrin; Octa-6-iodo-γ-cyclodextrin; γ-Cyclodextrin Iodide Derivative
EINECS	Contact for details

Quality Control

Our Octakis-6-Iodo-6-Deoxy-γ-Cyclodextrin is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with key parameters such as assay (HPLC), residual solvent content, and identification (IR, NMR). Specifications can be aligned with research or cGMP standards upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.