Description

Rimonabant Hydrochloride is a selective cannabinoid receptor type 1 (CB1) antagonist. This compound is a critical reference standard and active pharmaceutical ingredient (API) for research and development in metabolic and neurological pathways. It is primarily utilized by pharmaceutical companies, academic research institutions, and contract research organizations (CROs) for preclinical studies and analytical method development.

Application

• Pharmaceutical research and development as a reference standard for CB1 receptor antagonist studies.
• Preclinical investigation of potential therapeutic agents for obesity and metabolic disorders.
• Analytical method development and validation in quality control laboratories.
• Use as a high-purity chemical intermediate in the synthesis of novel chemical entities.
• Pharmacological research focusing on the endocannabinoid system and its role in appetite regulation.
• Biochemical studies for receptor binding assays and mechanism of action elucidation.

Basic Information

Product Name	Rimonabant Hydrochloride
CAS No.	158681-13-1
Molecular Formula	C22H21Cl3N4O • HCl
Molecular Weight	523.25 g/mol
Synonyms	SR141716A Hydrochloride; Acomplia (brand name); N-(Piperidin-1-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide hydrochloride; 5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide hydrochloride; CB1 Receptor Antagonist; Rimonabant HCl
EINECS	Contact for details

Quality Control

Our Rimonabant Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and mass spectrometry, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications and test results are provided to ensure traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.