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Ethyl Morphine 6-B-D-Glucuronide CAS NO 168074-32-6
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CAS No.:168074-32-6
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Ethyl Morphine 6-B-D-Glucuronide is a specific glucuronide metabolite of ethylmorphine, a semi-synthetic opioid. This high-purity reference standard is critical for analytical and research applications requiring precise quantification and structural confirmation. It is primarily utilized by pharmaceutical R&D laboratories, forensic toxicology units, and clinical research organizations engaged in drug metabolism and pharmacokinetic (DMPK) studies.
Application
- Pharmaceutical Reference Standard: Serves as a certified primary standard for the quantitative analysis of ethylmorphine and its metabolites in drug development.
- Forensic Toxicology: Used for the accurate identification and confirmation of ethylmorphine use in biological samples (e.g., urine, blood) for legal and workplace testing.
- Metabolite Research: Essential for in-vitro and in-vivo studies investigating the Phase II glucuronidation metabolic pathway of opioid compounds.
- Clinical Study Calibration: Employed to calibrate analytical instrumentation (HPLC-MS/MS, GC-MS) in clinical trials monitoring drug metabolism.
- Biomarker Development: Aids in the development and validation of specific biomarkers related to opioid metabolism and excretion.
- Quality Control (QC) Testing: Used by pharmaceutical manufacturers for internal QC of processes involving ethylmorphine-based products.
Basic Information
| Product Name | Ethyl Morphine 6-B-D-Glucuronide |
| CAS No. | 168074-32-6 |
| Molecular Formula | C25H31NO9 |
| Molecular Weight | 489.52 g/mol |
| Synonyms | Ethylmorphine 6-β-D-Glucuronide; 6-O-(β-D-Glucopyranuronosyl)ethylmorphine; Ethylmorphine Glucuronide; Ethylmorphine-6-glucuronide; 7,8-Didehydro-4,5α-epoxy-3-ethoxy-17-methylmorphinan-6α-ol 6-β-D-Glucopyranosiduronic Acid; NSC 758434; 6-β-Glucuronide of Ethylmorphine |
| EINECS | Contact for details |
Quality Control
Our Ethyl Morphine 6-B-D-Glucuronide is manufactured under strict quality control protocols suitable for research and analytical applications. Each batch is characterized using advanced spectroscopic and chromatographic techniques to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay results, and impurity profiles is provided with every shipment to support your compliance and research documentation needs.
Storage
Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept in a dry environment. For long-term storage, consider desiccants.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (IR) | Conforms to structure |
| Identification (HPLC) | Retention time matches reference standard |
| Purity (HPLC) | ≥ 95.0% |
| Water Content (KF) | ≤ 5.0% |
| Residue on Ignition | ≤ 0.5% |
| Heavy Metals | ≤ 20 ppm |
| Specific Optical Rotation | Contact for details |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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