Description

Ethyl Morphine 6-(Tri-o-Acetylglucuronide Methyl Ester) is a high-purity, chemically defined reference standard and synthetic intermediate. This compound is critical for analytical research, method development, and quality control in pharmaceutical and forensic laboratories. It is primarily utilized by researchers and quality assurance professionals in the pharmaceutical, forensic toxicology, and analytical chemistry sectors for precise calibration and metabolite identification.

Application

• Pharmaceutical Reference Standard: Used for the quantitative and qualitative analysis of ethyl morphine and its metabolites in drug development and quality control (QC) testing.
• Forensic Toxicology: Serves as a critical calibrant and control material in the detection and confirmation of opioid use in biological samples via LC-MS/MS and GC-MS.
• Metabolite Research: Acts as a key synthetic intermediate or standard for studying the glucuronidation metabolic pathway of ethyl morphine.
• Analytical Method Development: Essential for developing, validating, and verifying chromatographic and spectroscopic methods in compliance with GLP and ICH guidelines.
• Biochemical Research: Used in studies investigating opioid receptor interactions, metabolic enzyme kinetics (e.g., UGT enzymes), and pharmacokinetics.

Basic Information

Product Name	Ethyl Morphine 6-(Tri-o-Acetylglucuronide Methyl Ester)
CAS No.	168074-31-5
Molecular Formula	C34H39NO13
Molecular Weight	669.68 g/mol
Synonyms	Ethylmorphine 6-Glucuronide Triacetate Methyl Ester; 7,8-Didehydro-4,5-epoxy-3-ethoxy-17-methylmorphinan-6-ol 6-(Tri-O-acetyl-β-D-glucopyranosid)uronate Methyl Ester; Ethylmorphine-6-β-D-glucuronide triacetate methyl ester; Ethyl Morphine Glucuronide Derivative; 6-O-(Methyl 2,3,4-tri-O-acetyl-β-D-glucopyranuronosyl)ethylmorphine
EINECS	Contact for details

Quality Control

Every batch of Ethyl Morphine 6-(Tri-o-Acetylglucuronide Methyl Ester) is manufactured and tested under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity suitable for use as a reference material. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and spectroscopic data is provided with each shipment to support your compliance and research needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label or COA. Keep the container in a dry, cool, and well-ventilated area.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Residual Solvents (GC)	Complies with ICH limits
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.