Description

Proteinase Inhibitor Ati CAS NO 167821-94-5 is a potent, synthetic small-molecule inhibitor designed to target and neutralize specific proteolytic enzyme activity. This compound is critical for ensuring experimental integrity and product stability by preventing unwanted protein degradation in sensitive biochemical processes. It is an essential reagent for researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors, where precise control over protease activity is paramount.

Application

• Biopharmaceutical Manufacturing: Used in cell culture media and downstream purification to protect therapeutic proteins (e.g., monoclonal antibodies, enzymes) from proteolytic cleavage.
• Diagnostic Kit Formulation: Incorporated as a stabilizing agent in ELISA kits, lateral flow assays, and other in-vitro diagnostics to preserve antibody and antigen integrity.
• Research & Development: A key tool in biochemical and cell-based assays to study protease function, signal transduction pathways, and apoptosis.
• Sample Preparation: Added to tissue homogenates, cell lysates, and serum/plasma samples to prevent protein degradation during extraction and analysis.
• Enzyme Storage & Stabilization: Employed in the formulation of commercial enzyme preparations to maintain long-term activity and shelf-life.

Basic Information

Product Name	Proteinase Inhibitor Ati
CAS No.	167821-94-5
Molecular Formula	C16H21N3O4S
Molecular Weight	351.42 g/mol
Synonyms	Ati; 4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride (AEBSF.HCl); AEBSF; Pefabloc SC; 4-(2-Aminoethyl)benzenesulfonyl fluoride, hydrochloride; Protease Inhibitor Ati; Serine Protease Inhibitor Ati; Benzenesulfonyl fluoride, 4-(2-aminoethyl)-, hydrochloride
EINECS	Contact for details

Quality Control

Our Proteinase Inhibitor Ati is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and mass spectrometry, to ensure identity, potency, and consistency. Certificates of Analysis (COA) with detailed specifications are provided and can be tailored to meet specific GMP, ISO, or research-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. The product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric moisture. For long-term storage, consider desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Biological Activity	≥ 95% of reference standard

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.